Advanced Search Abstract The female European mole Talpa europaea presents a vivid paradox in relation to our contemporary understanding of mammalian sexual differentiation.
Cholesterol is the parent compound from which all steroid hormones are synthesized. The product pregnenolone formed from cholesterol serves as precursor for mineralocorticoids, glucocorticoids, as well as dehydroepiandrosterone DHEA and its derived sexual hormones.
DHEA assumes the prohormone status of a predominant endogenous precursor and a metabolic intermediate in ovarian follicular steroidogenesis.
DHEA supplementation has been used to enhance ovarian reserve. Steroids like estradiol and testosterone have long been contemplated to play important roles in regulating meiotic maturation of oocytes in conjunction with gonadotropins.
In summary, Wt1 regulates the development of FLC and interstitial progenitor cell lineages through Notch signaling, and it also plays a role in PMC development. Collectively, these effects confer fetal testis compartmentalization.
R-spondin 1 has been clearly established as a candidate for mammalian ovary determination. Conversely, very little information is available on the expression and role of R-spondin 1 during testicular morphogenesis.
This study aims to clarify the distribution pattern of R-spondin 1 and other partners of its machinery during the entire period of testicular morphogenesis and to indicate the role of this system in testicular development. Our whole mount immunofluorescence results clearly demonstrate that R-spondin 1 is always detectable in the testicular coelomic partition, where testicular vasculature is organized, while Dickkopf-1 is never detectable in this area.
Moreover, organ culture experiments of embryonic male UGRs demonstrated that Dickkopf-1 acted as an inhibitor of testis vasculature formation. Consistent with this observation, real-time PCR analyses demonstrated that DKK1 is able to slightly but significantly decrease the expression level of the endothelial marker Pecam1.
Here we show a role for the Gadd45g protein in this primary sex differentiation. These results identify Gadd45g as a candidate gene for male infertility and 46,XY sex reversal in humans. Therefore the list of references do not reflect any editorial selection of material based on content or relevance.
References appear in this list based upon the date of the actual page viewing. References listed on the rest of the content page and the associated discussion page listed under the publication year sub-headings do include some editorial selection based upon both relevance and availability.
J Magn Reson Imaging: This may represent an underlying ancestral mechanism by which oestrogen promotes ovarian development in the gonads of nonmammalian vertebrates. Furthermore, oestrogen may retain this function in adult female mammals to maintain granulosa cell fate in the differentiated ovary by suppressing nuclear translocation of the SOX9 protein.
Our results are interpreted as follows: This is in opposition to the previous hypothesis of Werdelin and Nilsonne that the scrotum may have evolved before the origin of mammals and then repeatedly disappeared in many groups including monotremes.
We suggest that the scrotum evolved at least twice during the evolutionary history of mammals, within Marsupialia and Boreoeutheria, and has subsequently been lost by many groups; this trend is especially strong in Laurasiatheria.
We suggest that the recent diversity in testicular position within mammals is the result of multiple selection pressures stemming from the need to provide conditions suitable for sperm development and storage, or to protect the male gonads from excessive physical and physiological disturbance.In the testis, seminiferous tubules are surrounded by the interstitial tissue.
In this tissue, there is a type of cell known after a scientist, Leydig. What are the functions of testis and ovary? Functions of the Testis: (a) They produce male gametes called spermatozoa by the process of spermatogenesis. (b) The leydig cells of the seminiferous tubules secrete the male sex hormone called testosterone.
Testosterone aids the development of secondary sex characteristics in males. Functions of the ovary: (a) They produce female gametes called ova by the process of oogenesis. This chapter deals with the normal macroscopic, microscopic, and ultrastructural morphology of the human ovary, and its hormonal function.
It is a structure that is ovoid in shape and between four to six centimeters in length.
Histology of ovary 12, views. Share; Like; Download Farhana Jafri, Assistant professor anatomy at AIMC Histology Of Female Genital Tract dreyngerous.
histology of male reproductive system Subhajit Hajra. Histology of Testis by Dr Mohammad Manzoor Mashwani Mohammad Manzoor. histologic structure of female genital system wayan.